aflatoxins in iran: nature, hazards and carcinogenicity
نویسندگان
چکیده
many studies have shown that mycotoxin contamination of agricultural products is a challenge for individual's health especially in developing countries. improper production and storage of foods, prepare conditions for aflatoxin production in crops, especially rice, wheat, pistachio, walnut, almond, etc which are the main sources of foods for people. feeding livestock by contaminated bread is another way of human exposure to mycotoxins, especially aflatoxin and because of expensive methods for detecting and analyzing aflatoxin in laboratory; it is not measured in foods. this manuscript is a review of some iranian and noniranian reports about aflatoxin, its exposure ways, its adverse effect on human health and nutrition, as well as methods for reducing its exposure. based on studies on foods, aflatoxin exposure is high in iran. since livestock feeding by contaminated bread is one of the potential ways for milk contamination, we should control and reduce aflatoxin contamination by improving production process, storage condition and livestock feeding as soon as possible. pistachio is one of the most important exporting products of iran and to maintain iran's position in exporting of this product, specific regulations on lowering its contamination with aflatoxin should be considered seriously. finally, effective controlling of all food and feedstuffs which are vulnerable to aflatoxin contamination is necessary to prevent its effects.
منابع مشابه
Aflatoxins in Iran: Nature, Hazards and Carcinogenicity
Many studies have shown that mycotoxin contamination of agricultural products is a challenge for individual's health especially in developing countries. Improper production and storage of foods, prepare conditions for aflatoxin production in crops, especially rice, wheat, pistachio, walnut, almond, etc which are the main sources of foods for people. Feeding livestock by contaminated bread is an...
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Aflatoxins B! and G,, in single doses, were lethal and had similar relative potencies in the duckling (50% lethal dose, 0.73 mg/kg versus 1.18 mg/kg) and in the rat (50% lethal dose, 1.16 mg/kg versus 2 to 4 mg/kg). Aflatoxins B2 and G2 were less potent in the duckling (50% lethal dose, 1.76 mg/kg versus 2.83 mg/kg) and were nontoxic to rats at doses of 200 mg/kg. Aflatoxin BI induced hepatocel...
متن کاملStructure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs.
Aflatoxins B! and G,, in single doses, were lethal and had similar relative potencies in the duckling (50% lethal dose, 0.73 mg/kg versus 1.18 mg/kg) and in the rat (50% lethal dose, 1.16 mg/kg versus 2 to 4 mg/kg). Aflatoxins B2 and G2 were less potent in the duckling (50% lethal dose, 1.76 mg/kg versus 2.83 mg/kg) and were nontoxic to rats at doses of 200 mg/kg. Aflatoxin BI induced hepatocel...
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The influence of dietary protein content and dietary vitamin B,, supplement on the hepatotoxicity and carcinogenicity of aflatoxin in rat liver was studied. In animals fed a low-protein diet, aflatoxin induced extensive toxic and carcinogenic effects. Cirrhosis was significantly pre vented to a certain level by vitamin B,_administration, but the incidence of cholangiofibrosis and hyperplastic n...
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عنوان ژورنال:
iranian journal of public healthجلد ۴۰، شماره ۴، صفحات ۱-۳۰
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